Kinetics out-of Peripheral Muscle tissue Oxygenation Throughout a training Take to

Kinetics out-of Peripheral Muscle tissue Oxygenation Throughout a training Take to

To possess proportions, the new distances amongst the incident area together with dos detectors had been 31 mm and you can fifteen mm, which were selected since the a previous investigation showed that the maximum computing breadth towards the tissue blood regularity as well as oxygenation away from new intra-smooth muscle have been up to fifteen mm and you can 29 mm about epidermis of the skin, correspondingly. 27 To display you to subcutaneous fatty tissue got little affect the intramuscular hemodynamics and oxygenation proportions, i performed a beneficial differential formula regarding sized the new devices. The fresh new devices was in fact fixed which have recording once becoming secured having a plastic piece and you will synthetic. These types of analysis was basically imported into a computer in the a sample regularity of ten Hz via an analogue-to-electronic converter (NR500, Keyence, Osaka, Japan). The fresh new included and you may imply philosophy away from 31-next times was in fact determined making use of the analogue-to-digital converter’s software (Wave Logger 1.03, Keyence, Osaka, Japan). The newest indicate was determined by the dividing these thinking because of the inbuilt time.

Muscle Fresh air Extraction Price

Oxygen transport variables included DO2, V?O2, and the oxygen extraction rate (OER). It has been established that DO2 is determined by arterial oxygen content (CaO2) and cardiac output, whereas V?O2 is determined by CaO2, venous oxygen content (CVO2), and differences in cardiac output. OER is determined by the ratio of DO2 to V?O2. 28 In this study, CaO2 and CVO2 were calculated from SpO2, venous blood saturation (SVO2), PaO2, and mixed venous oxygen pressure (PvO2) with the following formulas:

C aO 2 = ( 1.34 ? Hb ? S pO dos ) + ( 0.003 ? P aO 2 ) C vO 2 = ( step one.34 ? Hb ? S vO 2 ) + ( 0.003 ? P vO dos )

The terms (0.003 ? PaO2) and (0.003 ? PvO2) are typically negligibly small, particularly because OER is calculated using the following formula:

OER = ( C aO dos ? C vO 2 ) / C aO 2 ? ( S pO 2 ? S vO 2 ) / S pO 2

Mathematical Research

Data analysis was performed using statistics software (SPSS 19.0, SPSS, Chicago, Illinois). The Kolmogorov-Smirnov test was used to evaluate the data distribution. We performed analyses with Pearson correlation coefficients (r) to examine the relationships between the V?O2 values from the exercise test and the means of oxy-Hb, deoxy-Hb, total Hb, StO2, SpO2, HR, or MOER for each 30-second interval during the test. After we confirmed significant correlations between V?O2 and HR, SpO2, StO2, or MOER, we obtained the slopes of HR/V?O2, SpO2/V?O2, StO2/V?O2, and MOER/V?O2 from the regression analysis. In some subjects, SpO2 was not normally distributed, but we performed the same analysis in order to estimate regression slopes in this study. We also analyzed the relationships between the peak V?O2 and the slopes of HR/V?O2, SpO2/V?O2, StO2/V?O2, and MOER/V?O2 using Pearson correlation coefficients. A P value of less than .05 was considered statistically significant.


In many of the subjects in this study, both the deoxy-Hb and total Hb levels gradually increased with exercise intensity, either immediately or during the test. In contrast, the levels of both oxy-Hb and StO2 gradually decreased during the test (Fig. 2). However, the oxy-Hb, deoxy-Hb, and StO2 levels changed somewhat during the test in subjects 2 and 6.

Relationships Between V?O2 and Peripheral Muscle Oxygenation, Heart Rate, and SpO2

We calculated the relationships between V?O2 and oxy-Hb, deoxy-Hb, total Hb, StO2, MOER, HR, and SpO2 per 30 seconds during the exercise test for each subject, using primary regression. V?O2 was negatively correlated with StO2 (r = ?0.473 to ?0.979, P = .001 to .047) and SpO2 (r = ?0.599 to ?0.977, P = .001 to .029). In contrast, V?O2 was positively correlated with deoxy-Hb (r = 0.706 to 0.978, P < .001), total Hb (r = 0.598 to 0.952, P = .001 to .039), MOER (r = 0.557 to 0.965, P = .001 to .047), and HR (r = 0.903 to 0.991, P < .001) of subjects. We found no obvious relationship between V?O2 and oxy-Hb; in some individuals, there was a eters (r = ?0.655 to ?0.977, P = .001 to .029), but there was no apparent correlation in subjects 2 (r = 0.068) or 6 (r = ?0.209) (Table 2).

Laisser un commentaire

Votre adresse e-mail ne sera pas publiée. Les champs obligatoires sont indiqués avec *